Holding onto a joker for as long as possible may be a good idea if an opponent is almost finished with their hand and has been discarding cards that might possibly form a sequence with that joker. Ocasino game app downloadn the other hand, if you start the game with a lot of jokers, think about strategically using them to create sets or pure sequences that will give you an advantage over your rivals. Learning to Use Jokes Effectively. Understanding how to use jokers to your advantage while also keeping in mind how they might help your opponents is essential to becoming proficient in this area of Indian Rummy.